Researchers found no evidence of a causal relationship between most drugs previously implicated in microscopic colitis risk — including nonsteroidal anti-inflammatory drugs (NSAIDs), proton-pump inhibitors, and statins — and researchers said a small association with selective serotonin receptor inhibitors could come down to surveillance bias. (Annals of Internal Medicine)
Use of SGLT2 inhibitors in patients on diuretic therapy for cirrhosis was associated with a 32% lower incidence of serious liver events, a propensity score-matched analysis found. (JAMA Network Open)
New York City gastroenterologist Zhi Alan Cheng, MD, pleaded guilty to sexually abusing sedated patients at his hospital and raping women who were unconscious at his home. (AP)
Maintaining a healthy lifestyle was linked with a lower risk of diverticulitis, an analysis involving four prospective cohort studies showed. (Gut)
In a cohort study with over two decades of follow-up, the risk for reflux recurrence following primary fundoplication for gastroesophageal reflux disease (GERD) was identical (17%) for patients with erosive or non-erosive GERD. (JAMA Network Open)
Proton-pump inhibitor use in menopausal women was linked to a longer-term risk of incident hypertension. (Journal of the American Heart Association)
The novel GLP-1/glucagon dual receptor agonist pemvidutide met its primary endpoint in a phase IIb trial of metabolic dysfunction-associated steatohepatitis (MASH), with MASH resolution without worsening of fibrosis in up to 59% of pemvidutide-treated patients versus 19% for the placebo recipients, Altimmune announced.
Researchers found that resmetirom (Rezdiffra) for MASH was not cost-effective at a willingness-to-pay threshold of $100,000 per quality-adjusted life-year. (JAMA Network Open)
Meanwhile, frequent hepatitis C virus testing among people who inject drugs was found to be cost-effective even in lower transmission settings. (JAMA Health Forum)
The American Gastroenterological Association applauded the Supreme Court’s Kennedy v. Braidwood decision, which preserves no-cost health insurance coverage for colorectal cancer and hepatitis C screening, as recommended by the U.S. Preventive Services Task Force.
A systematic review and meta-analysis looked at the use of wearables for patients with inflammatory bowel disease (IBD). (Clinical Gastroenterology and Hepatology)
Experts weighed in on the evaluation and management of glucocorticoid-induced adrenal insufficiency in IBD patients. (Inflammatory Bowel Diseases)
For patients with obesity undergoing endoscopy of the upper gastrointestinal tract, nasal continuous positive airway pressure can reduce the risk of hypoxia, a randomized trial found. (Clinical Gastroenterology and Hepatology)
